Peptidoglycan structure and architecture

被引:1648
作者
Vollmer, Waldemar [1 ]
Blanot, Didier [2 ]
de Pedro, Miguel A. [3 ]
机构
[1] Newcastle Univ, Sch Med, Inst Cell & Mol Biosci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[2] Univ Paris Sud, CNRS, UMR 8619, IBBMC, Orsay, France
[3] Univ Autonoma Madrid, CSIC, Ctr Biol mol Severo Ochoa, Madrid, Spain
关键词
peptidoglycan; murein; bacterial cell wall;
D O I
10.1111/j.1574-6976.2007.00094.x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The peptidoglycan (murein) sacculus is a unique and essential structural element in the cell wall of most bacteria. Made of glycan strands cross-linked by short peptides, the sacculus forms a closed, bag-shaped structure surrounding the cytoplasmic membrane. There is a high diversity in the composition and sequence of the peptides in the peptidoglycan from different species. Furthermore, in several species examined, the fine structure of the peptidoglycan significantly varies with the growth conditions. Limited number of biophysical data on the thickness, elasticity and porosity of peptidoglycan are available. The different models for the architecture of peptidoglycan are discussed with respect to structural and physical parameters.
引用
收藏
页码:149 / 167
页数:19
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