Photocontrolling peptide α helices

被引：182

作者：

Woolley, GA ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2005年 / 38卷 / 06期

关键词：

D O I：

10.1021/ar040091v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reversible optical control of protein structure and function offers the possibility of probing and manipulating individual proteins within the complex environment of a living cell. As a first step toward creating artificial photocontrolled proteins, we have designed and synthesized reversible, photocontrolled peptide a helices. Here, I attempt to summarize the lessons learned from that endeavor.

引用

页码：486 / 493

页数：8

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