In Vitro Activities of Anidulafungin and Other Antifungal Agents against Biofilms Formed by Clinical Isolates of Different Candida and Aspergillus Species

被引：62

作者：

Fiori, Barbara ^{[1
]}

Posteraro, Brunella ^{[1
]}

Torelli, Riccardo ^{[1
]}

Tumbarello, Mario ^{[2
]}

Perlin, David S. ^{[3
]}

Fadda, Giovanni ^{[1
]}

Sanguinetti, Maurizio ^{[1
]}

机构：

[1] Univ Cattolica Sacro Cuore, Ist Microbiol, I-00168 Rome, Italy

[2] Univ Cattolica Sacro Cuore, Inst Infect Dis, I-00168 Rome, Italy

[3] UMDNJ, New Jersey Med Sch, Publ Hlth Res Inst, Newark, NJ USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 06期

关键词：

ALBICANS BIOFILMS; FUNGAL BIOFILMS; FUMIGATUS; SUSCEPTIBILITY; PARAPSILOSIS; DRUGS; MODEL;

D O I：

10.1128/AAC.01569-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We tested the activities of anidulafungin and other antifungal agents against clinical isolates of different fungal species. For Candida species, high sessile MIC(90)s (SMIC(90)s) were obtained for fluconazole, voriconazole, and amphotericin B, whereas the anidulafungin SMIC(90)s were very low, as were those for caspofungin. Comparatively, for Aspergillus species, higher SMIC(90) values were obtained not only for amphotericin B and voriconazole but also for the echinocandins.

引用

页码：3031 / 3035

页数：5

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