Chlamydia trachomatis IncA is localized to the inclusion membrane and is recognized by antisera from infected humans and primates

被引:81
作者
Bannantine, JP
Stamm, WE
Suchland, RJ
Rockey, DD
机构
[1] Oregon State Univ, Dept Microbiol, Corvallis, OR 97331 USA
[2] Univ Washington, Sch Med, Div Allergy & Infect Dis, Seattle, WA 98195 USA
关键词
D O I
10.1128/IAI.66.12.6017-6021.1998
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Chlamydia psittaci produces a collection of proteins, termed IncA, IncB, and IncC, that are localized to the chlamydial inclusion membrane. In this report we demonstrate that IncA is also produced by Chlamydia trachomatis. C. trachomatis IncA is structurally similar to C. psittaci IncA and is also localized to the inclusion membrane. Immunoblot analysis demonstrated that sera from C. trachomatis-infected patients and from experimentally infected monkeys both recognized C. trachomatis IncA.
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页码:6017 / 6021
页数:5
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