Progress in myocardial regeneration and cell transplantation

被引：28

作者：

Fukuda, K ^{[1
]}

机构：

[1] Keio Univ, Sch Med, Dept Regenerat Med & Adv Cardiac Therapeut, Shinjuku Ku, Tokyo 1608582, Japan

来源：

CIRCULATION JOURNAL | 2005年 / 69卷 / 12期

关键词：

bone marrow mesenchymal stem cells; cardiomyocytes; cell transplantation; embryonic stem cells; heart failure; regenerative medicine;

D O I：

10.1253/circj.69.1431

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Embryonic stem cells and bone marrow mesenchymal stem cells can be induced to differentiate into cardiomyocytes. Techniques to purify and transplant regenerated cardiornyocytes have been developed, and transplanted regenerated cardiomyocytes are capable of residing in the heart of recipients for long periods. Advances in tissue engineering technology have enabled the production of cardiornyocyte cell sheets for transplantation treatment of heart failure, without the need for a donor, and this has now reached the preclinical stage. The treatment of heart failure using cytokines to mobilize stem cells has also been explored.

引用

收藏

页码：1431 / 1446

页数：16

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