Molecular iodine: a powerful catalyst for the easy and efficient synthesis of quinoxalines

被引：237

作者：

More, SV ^{[1
]}

Sastry, MNV ^{[1
]}

Wang, CC ^{[1
]}

Yao, CF ^{[1
]}

机构：

[1] Natl Taiwan Normal Univ, Dept Chem, Taipei 116, Taiwan

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 37期

关键词：

1,2-diketones; quinoxalines; iodine; catalytic amount; ecofriendly process;

D O I：

10.1016/j.tetlet.2005.07.026

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various biologically important quinoxaline derivatives were efficiently synthesized in excellent yields using inexpensive, nontoxic, and readily available bench top chemical, iodine in catalytic amount (10 mol %). Besides this, a systematic study was carried out to evaluate parameters such as solvent and catalyst loading. Several aromatic as well as aliphatic 1,2-diketones and aromatic 1,2-diamines, such as substituted phenylene diamines, tetra amines were further subjected to condensation using catalytic amounts of iodine to afford the products in excellent yield. (c) 2005 Published by Elsevier Ltd.

引用

页码：6345 / 6348

页数：4

共 42 条

[1] Synthesis and antimicrobial activities of some novel quinoxalinone derivatives [J].