High-sensitivity analysis of cyanide by capillary electrophoresis with fluorescence detection

被引：29

作者：

Chinaka, S

Tanaka, S

Takayama, N

Tsuji, N

Takou, S

Ueda, K

机构：

[1] Ishikawa Prefectural Police Headquarters, Forens Sci Lab, Kanazawa, Ishikawa 9208553, Japan

[2] Kanazawa Univ, Fac Engn, Dept Chem & Chem Engn, Kanazawa, Ishikawa 9208667, Japan

[3] Hamamatsu Ind Res Inst, Adv & Fundamental Technol Dept, Hamamatsu, Shizuoka 4312103, Japan

来源：

ANALYTICAL SCIENCES | 2001年 / 17卷 / 05期

关键词：

D O I：

10.2116/analsci.17.649

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A capillary electrophoretic method for a high-sensitivity analysis of cyanide has been developed. Cyanide was derivatized with 2,3-naphthalenedialdehyde and taurine to give a fluorescent product of 1-cyanobenz[f]isoindole. This compound was detected with high sensitivity by fluorescence detection. The detection limit was 0.1 ng/mL, and the calibration curve was linear over the range 0.1 - 200 ng/mL. The precision of the migration time of within-run assays (n = 6) of 1 ng/mL cyanide standard solution was 0.14%. The precision of the peak area for the same runs was 1.0%. This method was applicable to blood analysis. Detection of the cyanide derivative by UV was also examined.

引用

页码：649 / 652

页数：4

共 9 条

[1] Simultaneous determination of cyanide and thiocyanate in blood by ion chromatography with fluorescence and ultraviolet detection [J].