Mechanical properties of powders for compaction and tableting: an overview

被引：106

作者：

Jain, S ^{[1
]}

机构：

[1] Glaxo Wellcome Inc, Pharmaceut & Chem Anal, Res Triangle Pk, NC 27709 USA

来源：

PHARMACEUTICAL SCIENCE & TECHNOLOGY TODAY | 1999年 / 2卷 / 01期

关键词：

D O I：

10.1016/S1461-5347(98)00111-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review provides an insight into mechanical properties that are critical to understanding powder processing for tableting. Various parameters that reflect these basic fundamental properties of powder and their evaluation by different techniques are described. Some recent examples in which these techniques are used in drug substance selection, formulation optimization or scale-up are also provided.

引用

页码：20 / 31

页数：12

共 80 条

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