Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study

被引:641
作者
Soriguer, F. [1 ]
Goday, A. [2 ]
Bosch-Comas, A. [3 ]
Bordiu, E. [4 ]
Calle-Pascual, A. [5 ]
Carmena, R. [6 ]
Casamitjana, R. [7 ]
Castano, L. [8 ]
Castell, C. [9 ]
Catala, M. [6 ]
Delgado, E. [10 ]
Franch, J. [11 ]
Gaztambide, S. [8 ]
Girbes, J. [12 ]
Gomis, R. [3 ,13 ]
Gutierrez, G. [8 ]
Lopez-Alba, A. [14 ]
Martinez-Larrad, M. T. [15 ]
Menendez, E. [10 ]
Mora-Peces, I. [16 ]
Ortega, E. [3 ,13 ]
Pascual-Manich, G.
Rojo-Martinez, G. [1 ]
Serrano-Rios, M. [15 ]
Valdes, S. [1 ]
Vazquez, J. A. [17 ]
Vendrell, J. [18 ]
机构
[1] Hosp Univ Carlos Haya, Dept Endocrinol & Nutr, Malaga 29009, Spain
[2] Hosp del Mar, Dept Endocrinol & Nutr, Barcelona, Spain
[3] Inst Invest Biomed August Pi i Sunyer IDIBAPS, Barcelona, Spain
[4] Hosp Univ S Carlos Madrid, Lab Endocrinol, Madrid, Spain
[5] Hosp Univ S Carlos Madrid, Dept Endocrinol & Nutr, Madrid, Spain
[6] Hosp Clin Univ Valencia, Dept Med & Endocrinol, Valencia, Spain
[7] Univ Hosp Clin Barcelona, Biomed Diagnost Ctr, Barcelona, Spain
[8] Univ Basque Country, Hosp Univ Cruces, Diabet Res Grp, Baracaldo, Spain
[9] Autonomous Govt Catalonia, Dept Hlth, Publ Hlth Div, Barcelona, Spain
[10] Univ Oviedo, Hosp Cent Asturias, Dept Endocrinol & Nutr, E-33080 Oviedo, Spain
[11] IDIAP Fundacio Jordi Gol, Unitat Suport Recerca, Red GEDAPS, EAP Raval Sud,Inst Catala Salut, Barcelona, Spain
[12] Hosp Arnau Vilanova, Diabet Unit, Valencia, Spain
[13] Univ Barcelona, Hosp Clin Barcelona, Endocrinol & Diabet Unit, Barcelona, Spain
[14] Spanish Diabet Soc, Madrid, Spain
[15] Hosp Univ S Carlos Madrid, Lipids & Diabet Lab, Madrid, Spain
[16] Hosp Nuestra Senora de los Reyes, Emergency Serv, Tenerife, Spain
[17] Minist Hlth, Madrid, Spain
[18] Hosp Univ Joan XXIII, Dept Endocrinol & Nutr, Inst Invest Sanitaries Pere Virgili, Tarragona, Spain
关键词
Epidemiology; Prevalence; Spain; Type 2 diabetes mellitus;
D O I
10.1007/s00125-011-2336-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The Di@bet.es Study is the first national study in Spain to examine the prevalence of diabetes and impaired glucose regulation. A population-based, cross-sectional, cluster sampling study was carried out, with target population being the entire Spanish population. Five thousand and seventy-two participants in 100 clusters (health centres or the equivalent in each region) were randomly selected with a probability proportional to population size. Participation rate was 55.8%. Study variables were a clinical and demographic structured survey, lifestyle survey, physical examination (weight, height, BMI, waist and hip circumference, blood pressure) and OGTT (75 g). Almost 30% of the study population had some carbohydrate disturbance. The overall prevalence of diabetes mellitus adjusted for age and sex was 13.8% (95% CI 12.8, 14.7%), of which about half had unknown diabetes: 6.0% (95% CI 5.4, 6.7%). The age- and sex-adjusted prevalence rates of isolated impaired fasting glucose (IFG), isolated impaired glucose tolerance (IGT) and combined IFG-IGT were 3.4% (95% CI 2.9, 4.0%), 9.2% (95% CI 8.2, 10.2%) and 2.2% (95% CI 1.7, 2.7%), respectively. The prevalence of diabetes and impaired glucose regulation increased significantly with age (p < 0.0001), and was higher in men than in women (p < 0.001). The Di@bet.es Study shows, for the first time, the prevalence rates of diabetes and impaired glucose regulation in a representative sample of the Spanish population.
引用
收藏
页码:88 / 93
页数:6
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