Number needed to treat (NNT)

被引：34

作者：

Cordell, WH ^{[1
]}

机构：

[1] Methodist Hosp, Emergency Med & Trauma Ctr, Clarian Hlth Partners, Indianapolis, IN 46206 USA

来源：

ANNALS OF EMERGENCY MEDICINE | 1999年 / 33卷 / 04期

关键词：

D O I：

10.1016/S0196-0644(99)70308-2

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Because decisions regarding therapy are so common in clinical practice, the application of number needed to treat (NNT) is one of the most important evidence-based medicine skills to be acquired. NNT provides a clinically useful "yardstick" of the effort required to have a beneficial outcome or prevent a bad outcome with a therapy. A brief overview of the concept, derivation, and application of NNT is presented.

引用

页码：433 / 436

页数：4

共 10 条

[1]

ALTMAN DG, 1996, EVIDENCE BASED MED, V1, P102

[2]

Chatellier G, 1996, BRIT MED J, V312, P426

[3] AN ASSESSMENT OF CLINICALLY USEFUL MEASURES OF THE CONSEQUENCES OF TREATMENT [J].

LAUPACIS, A ;

SACKETT, DL ;

ROBERTS, RS .

NEW ENGLAND JOURNAL OF MEDICINE, 1988, 318 (26) :1728-1733

[4] TISSUE-PLASMINOGEN ACTIVATOR FOR ACUTE ISCHEMIC STROKE [J].

MARLER, JR ;

BROTT, T ;

BRODERICK, J ;

KOTHARI, R ;

ODONOGHUE, M ;

BARSAN, W ;

TOMSICK, T ;

SPILKER, J ;

MILLER, R ;

SAUERBECK, L ;

JARRELL, J ;

KELLY, J ;

PERKINS, T ;

MCDONALD, T ;

RORICK, M ;

HICKEY, C ;

ARMITAGE, J ;

PERRY, C ;

THALINGER, K ;

RHUDE, R ;

SCHILL, J ;

BECKER, PS ;

HEATH, RS ;

ADAMS, D ;

REED, R ;

KLEI, M ;

HUGHES, S ;

ANTHONY, J ;

BAUDENDISTEL, D ;

ZADICOFF, C ;

RYMER, M ;

BETTINGER, I ;

LAUBINGER, P ;

SCHMERLER, M ;

MEIROSE, G ;

LYDEN, P ;

RAPP, K ;

BABCOCK, T ;

DAUM, P ;

PERSONA, D ;

BRODY, M ;

JACKSON, C ;

LEWIS, S ;

LISS, J ;

MAHDAVI, Z ;

ROTHROCK, J ;

TOM, T ;

ZWEIFLER, R ;

DUNFORD, J ;

ZIVIN, J .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (24) :1581-1587

[5] Using numerical results from systematic reviews in clinical practice [J].

McQuay, HJ ;

Moore .

ANNALS OF INTERNAL MEDICINE, 1997, 126 (09) :712-720

[6]

ROWE BH, 1998, COCHRANE DATABASE SY, V3, P3

[7]

Sackett D.L., 1997, ACP J CLUB, V127, pA15

[8]

Sackett D.L., 1997, Evidence-Based Medicine: How to Practice and Teach EBM

[9] What is confidence? .1. The use and interpretation of confidence intervals [J].

Young, KD ;

Lewis, RJ .

ANNALS OF EMERGENCY MEDICINE, 1997, 30 (03) :307-310

[10] What is confidence? .2. Detailed definition and determination of confidence intervals [J].

Young, KD ;

Lewis, RJ .

ANNALS OF EMERGENCY MEDICINE, 1997, 30 (03) :311-318

← 1 →