Ionic liquids in embalming and tissue preservation. Can traditional formalin-fixation be replaced safely?

被引：74

作者：

Majewski, P

Pernak, A

Grzymislawski, M

Iwanik, K

Pernak, J

机构：

[1] Poznan Univ Tech, Dept Chem Technol, PL-60965 Poznan, Poland

[2] Poznan Univ Med Sci, Poznan, Poland

来源：

ACTA HISTOCHEMICA | 2003年 / 105卷 / 02期

关键词：

ionic liquids; formalin; embalming; tissue preservation;

D O I：

10.1078/0065-1281-00707

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Ionic liquids (ILs) can be used for embalming and tissue preservation. ILs does not cause tissue damage and the tissue colour remains unaltered after treatment. Microscopical morphology of tissues fixed in ILs is of better quality than that of tissues fixed in formalin. Tissue preservation depends on the type of ILs. Best results were obtained with 1-methyl-3-octyloxymethylimidazolium tetrafluoroborate, the density of which resembles that of water. The salt is nonvaporous and when used as a formalin substitute, it eliminates health hazards in the pathological laboratory.

引用

页码：135 / 142

页数：8

共 30 条

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