Enzymatic fucosylation of non-natural trisaccharides with cloned fucosyltransferase VI

被引：33

作者：

Baisch, G ^{[1
]}

Ohrlein, R ^{[1
]}

Katopodis, A ^{[1
]}

Ernst, B ^{[1
]}

机构：

[1] CIBA GEIGY AG,CENT RES LABS,CH-4002 BASEL,SWITZERLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 07期

关键词：

D O I：

10.1016/0960-894X(96)00119-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Non-natural sialyl-lactosamine derivatives are subjected to enzymatic fucosylation with cloned fucosyltransferase VI, The enzyme tolerates a wide range of accepters, spanning from small and bulky aliphatic as well as charged and sulfonamide replacements of the natural N-acetyl residue. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：759 / 762

页数：4

共 28 条

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