Expression of GAP-43 in the retina of rats following protracted illumination

被引：6

作者：

López-Costa, JJ ^{[1
]}

Goldstein, J ^{[1
]}

Mangeaud, M ^{[1
]}

Saavedra, JP ^{[1
]}

机构：

[1] Univ Buenos Aires, Fac Med, Inst Biol Celular & Neurociencia Prof E De Robert, RA-1121 Buenos Aires, DF, Argentina

来源：

BRAIN RESEARCH | 2001年 / 900卷 / 02期

关键词：

GAP-43; illumination; photoreceptor; rat; regeneration; retina;

D O I：

10.1016/S0006-8993(01)02324-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Distribution of GAP-43 was studied in the retinas of rats after continuous illumination followed by different darkness periods. GAP-43 immunoreactivity was maximum in regenerating outer photoreceptor segments of rats kept in total darkness for 10 days, while in the inner plexiform layer, immunoreactivity was maximum immediately after illumination. Changes in GAP-43 expression could participate in retinal repair/regeneration after light-induced damage. (C) 2001 Published by Elsevier Science B.V.

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收藏

页码：332 / 336

页数：5

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