Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia

被引:56
作者
Bains, T. [1 ]
Heinrich, M. C. [1 ,2 ,3 ]
Loriaux, M. M. [3 ,4 ]
Beadling, C. [1 ,2 ,3 ]
Nelson, D. [3 ]
Warrick, A. [3 ]
Neff, T. L. [3 ]
Tyner, J. W. [3 ]
Dunlap, J. [3 ,4 ]
Corless, C. L. [3 ,4 ]
Fan, G. [3 ,4 ]
机构
[1] Oregon Hlth & Sci Univ, Dept Hematol & Oncol, Portland, OR 97201 USA
[2] VA Med Ctr, Dept Hematol & Oncol, Portland, OR USA
[3] Oregon Hlth & Sci Univ, Knight Canc Inst, Portland, OR 97201 USA
[4] Oregon Hlth & Sci Univ, Dept Pathol, Portland, OR 97201 USA
关键词
ACUTE MEGAKARYOBLASTIC LEUKEMIA; OF-FUNCTION MUTATIONS; DOWN-SYNDROME; IL7R;
D O I
10.1038/leu.2012.74
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
引用
收藏
页码:2144 / 2146
页数:3
相关论文
共 15 条
[1]
Multiplex Mutation Screening by Mass Spectrometry Evaluation of 820 Cases from a Personalized Cancer Medicine Registry [J].
Beadling, Carol ;
Heinrich, Michael C. ;
Warrick, Andrea ;
Forbes, Erin M. ;
Nelson, Dylan ;
Justusson, Emily ;
Levine, Judith ;
Neff, Tanaya L. ;
Patterson, Janice ;
Presnell, Ajia ;
McKinley, Arin ;
Winter, Laura J. ;
Dewey, Christie ;
Harlow, Amy ;
Barney, Oscar ;
Druker, Brian J. ;
Schuff, Kathryn G. ;
Corless, Christopher L. .
JOURNAL OF MOLECULAR DIAGNOSTICS, 2011, 13 (05) :504-513
[2]
The specificity of JAK3 kinase inhibitors [J].
Changelian, Paul S. ;
Moshinsky, Deborah ;
Kuhn, Cyrille F. ;
Flanagan, Mark E. ;
Munchhof, Michael J. ;
Harris, Thomas M. ;
Doty, Jonathan L. ;
Sun, Jianmin ;
Kent, Craig R. ;
Magnuson, Kelly S. ;
Perregaux, David G. ;
Sawyer, Perry S. ;
Kudlacz, Elizabeth M. .
BLOOD, 2008, 111 (04) :2155-2157
[3]
Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models [J].
Cornejo, Melanie G. ;
Kharas, Michael G. ;
Werneck, Miriam B. ;
Le Bras, Severine ;
Moore, Sandra A. ;
Ball, Brian ;
Beylot-Barry, Marie ;
Rodig, Scott J. ;
Aster, Jon C. ;
Lee, Benjamin H. ;
Cantor, Harvey ;
Merlio, Jean-Philippe ;
Gilliland, D. Gary ;
Mercher, Thomas .
BLOOD, 2009, 113 (12) :2746-2754
[4]
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia [J].
Flex, Elisabetta ;
Petrangeli, Valentina ;
Stella, Lorenzo ;
Chiaretti, Sabina ;
Hornakova, Tekla ;
Knoops, Laurent ;
Ariola, Cristina ;
Fodale, Valentina ;
Clappier, Emmanuelle ;
Paoloni, Francesca ;
Martinelli, Simone ;
Fragale, Alessandra ;
Sanchez, Massimo ;
Tavolaro, Simona ;
Messina, Monica ;
Cazzaniga, Giovanni ;
Camera, Andrea ;
Pizzolo, Giovanni ;
Tornesello, Assunta ;
Vignetti, Marco ;
Battistini, Angela ;
Cave, Helene ;
Gelb, Bruce D. ;
Renauld, Jean-Christophe ;
Biondi, Andrea ;
Constantinescu, Stefan N. ;
Foa, Robin ;
Tartaglia, Marco .
JOURNAL OF EXPERIMENTAL MEDICINE, 2008, 205 (04) :751-758
[5]
Prevalence and clinical correlates of JAK2 mutations in Down syndrome acute lymphoblastic leukaemia [J].
Gaikwad, Amos ;
Rye, Cassia L. ;
Devidas, Meenakshi ;
Heerema, Nyla A. ;
Carroll, Andrew J. ;
Izraeli, Shai ;
Plon, Sharon E. ;
Basso, Giuseppe ;
Pession, Andrea ;
Rabin, Karen R. .
BRITISH JOURNAL OF HAEMATOLOGY, 2009, 144 (06) :930-932
[6]
Jak1 Has a Dominant Role over Jak3 in Signal Transduction through γc-Containing Cytokine Receptors [J].
Haan, Claude ;
Rolvering, Catherine ;
Raulf, Friedrich ;
Kapp, Manuela ;
Drueckes, Peter ;
Thoma, Gebhard ;
Behrmann, Iris ;
Zerwes, Hans-Guenter .
CHEMISTRY & BIOLOGY, 2011, 18 (03) :314-323
[7]
ALL-associated JAK1 mutations confer hypersensitivity to the antiproliferative effect of type I interferon [J].
Hornakova, Tekla ;
Chiaretti, Sabina ;
Lemaire, Muriel M. ;
Foa, Robin ;
Ben Abdelali, Raouf ;
Asnafi, Vahid ;
Tartaglia, Marco ;
Renauld, Jean-Christophe ;
Knoops, Laurent .
BLOOD, 2010, 115 (16) :3287-3295
[8]
Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers [J].
Jeong, Eun Goo ;
Kim, Min Sung ;
Nam, Hyo Kyung ;
Min, Chang Ki ;
Lee, Seok ;
Chung, Yeun Jun ;
Yoo, Nam Jin ;
Lee, Sug Hyung .
CLINICAL CANCER RESEARCH, 2008, 14 (12) :3716-3721
[9]
Absence of gain-of-function JAK1 and JAK3 mutations in adult T cell leukemia/lymphoma [J].
Kameda, T. ;
Shide, K. ;
Shimoda, H. K. ;
Hidaka, T. ;
Kubuki, Y. ;
Katayose, K. ;
Taniguchi, Y. ;
Sekine, M. ;
Kamiunntenn, A. ;
Maeda, K. ;
Nagata, K. ;
Matsunaga, T. ;
Shimoda, K. .
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2010, 92 (02) :320-325
[10]
Activating mutations in human acute megakaryoblastic leukemia [J].
Malinge, Sebastien ;
Ragu, Christine ;
Della-Valle, Veronique ;
Pisani, Didier ;
Constantinescu, Stefan N. ;
Perez, Christelle ;
Villeval, Jean-Luc ;
Reinhardt, Dirk ;
Landman-Parker, Judith ;
Michaux, Lucienne ;
Dastugue, Nicole ;
Baruchel, Andre ;
Vainchenker, William ;
Bourquin, Jean-Pierre ;
Penard-Lacronique, Virginie ;
Bernard, Olivier A. .
BLOOD, 2008, 112 (10) :4220-4226