Damage to Pseudomonas aeruginosa PAO1 bacteriophage F116 DNA by biocides

被引：28

作者：

Maillard, JY

Beggs, TS

Day, MJ

Hudson, RA

Russell, AD

机构：

[1] UNIV WALES COLL CARDIFF,WELSH SCH PHARM,CARDIFF CF1 3XF,S GLAM,WALES

[2] UNIV WALES COLL CARDIFF,SCH PURE & APPL BIOL,CARDIFF CF1 3XF,S GLAM,WALES

[3] UNILEVER RES,SHARNBROOK,BEDS,ENGLAND

[4] LEVER IND DEV & APPLICAT CTR,MAARSSEN,NETHERLANDS

来源：

JOURNAL OF APPLIED BACTERIOLOGY | 1996年 / 80卷 / 05期

关键词：

D O I：

10.1111/j.1365-2672.1996.tb03254.x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The mechanism of action of biocides against viruses has not been widely studied, although two main targets are viral proteins (capsids, enzymes) and the viral genome. This study was undertaken in order to investigate the efficacy of several disinfectants against the nucleic acid of the Pseudomonas aeruginosa PAO bacteriophage F116. Of all the biocides tested, only peracetic acid affected significantly the phage genome. However, it is not clear whether the nucleic acid was damaged inside the phage capsid or when released into the surrounding medium.

引用

页码：540 / 544

页数：5

共 20 条

[1] ACTIVITY OF GLUTARALDEHYDE AT LOW CONCENTRATIONS (GREATER-THAN 2-PERCENT) AGAINST POLIOVIRUS AND ITS RELEVANCE TO GASTROINTESTINAL ENDOSCOPE DISINFECTION PROCEDURES [J].