DNA-templated metal catalysis

被引：86

作者：

Brunner, J ^{[1
]}

Mokhir, A ^{[1
]}

Kraemer, R ^{[1
]}

机构：

[1] Heidelberg Univ, Inst Anorgan Chem, D-69120 Heidelberg, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 41期

关键词：

D O I：

10.1021/ja0365429

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Hydrolysis of an ester substrate by a CuII complex catalyst, both attached to oligo-peptide nucleic acids (PNA), is accelerated up to 485-fold in the presence of a complementary DNA template. The approach combines the sequence selectivity of DNA-templated reactions with signal amplification by multiple turnover and the versatility of metal catalysis. Copyright © 2003 American Chemical Society.

引用

页码：12410 / 12411

页数：2

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