A stereochemical study of optically active thiazolidines

被引：14

作者：

Cruz, A

Vásquez-Badillo, A

Ramos-García, I

Contreras, R

机构：

[1] IPN, Ctr Invest & Estudios Avanzados, Dept Quim, Mexico City 07000, DF, Mexico

[2] IPN, Unidad Profes Interdisciplinaria Biotecnol, Dept Quim, Mexico City 07738, DF, Mexico

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(01)00117-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We report a stereochemical study of a series of free N-H and N-methylated 1,3-thiazolidines heating H or CH, at C-(2). These compounds were readily prepared from ephedrine and pseudoephedrines. The stereochemistry of the compounds under study was deduced using H-1 and C-13 NMR spectroscopy. Two isomers were found for compounds having a methyl group at C-(2) (i.e. C-(2)HCH3): interconversion of these isomers, presumably via a non-cyclic zwitterionic intermediate, was observed. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：711 / 717

页数：7

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