A new simple and quantitative synthesis of alpha-aminoacid-N-carboxyanhydrides (oxazolidines-2,5-dione)

被引：63

作者：

Collet, H

Bied, C

Mion, L

Taillades, J

Commeyras, A

机构：

[1] Lab. Organisation m. E. et M. F., Associe au CNRS Univ. de M. II, F-34095 Montpellier Cédex 5, Place E. Bataillon

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(96)01974-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitrosation of chiral N-cartarnoylaminoacids with a mixture of NO and O-2 gives, with the same con figuration and in quantitative yield the corresponding alpha-aminoacid-N-carboxyanhydrides (NCA), well known precursors of peptides. The by products of this reaction are N-2 and H2O. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：9043 / 9046

页数：4

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