Hematopoietic lineage commitment:: miRNAs add specificity to a widely expressed transcription factor

被引：18

作者：

Garcia, Paloma ^{[1
]}

Frampton, Jon ^{[1
]}

机构：

[1] Univ Birmingham, Sch Med, Inst Biomed Res, Birmingham B15 2TT, W Midlands, England

来源：

DEVELOPMENTAL CELL | 2008年 / 14卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/j.devcel.2008.05.011

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

MicroRNAs are important regulators of normal and malignant hematopoiesis. A paper by Lu et al. in this issue of Developmental Cell demonstrates how one microRNA, miR-150, plays a critical role in commitment of the erythroid-megakaryocyte progenitor by modulating the level of the widely expressed transcription factor MYB (or c-Myb).

引用

页码：815 / 816

页数：2

共 10 条

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