Ovarian tissue banking for cancer patients - To do or not to do?

被引：30

作者：

Kim, SS ^{[1
]}

机构：

[1] Eulji Univ, Sch Med, Dept Obstet & Gynecol, Seoul, South Korea

来源：

HUMAN REPRODUCTION | 2003年 / 18卷 / 09期

基金：

新加坡国家研究基金会;

关键词：

cancer; cryopreservation; fertility preservation; ovarian tissue; transplantation;

D O I：

10.1093/humrep/deg381

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A large proportion of childhood and young cancer patients will lose their fertility after aggressive cancer therapy because of the gonadotoxicities of chemotherapy and radiotherapy. One of the strategies to preserve fertility for those facing premature ovarian failure is ovarian tissue banking. We are seeing a growing enthusiasm about this emerging technology. At the same time, scepticism is prevalent, as the efficacy of ovarian tissue banking for fertility restoration in humans has not yet been proved. However, there is ample evidence of its efficacy in animal studies. Ovarian tissue banking requires further investigations and should be considered experimental in humans at present.

引用

页码：1759 / 1761

页数：3

共 19 条

[1] Orthotopic and heterotopic autografts of frozen-thawed ovarian cortex in sheep [J].

Aubard, Y ;

Piver, P ;

Cognié, Y ;

Fermeaux, V ;

Poulin, N ;

Driancourt, MA .

HUMAN REPRODUCTION, 1999, 14 (08) :2149-2154

[2] Long-term ovarian function in sheep after ovariectomy and transplantation of autografts stored at -196 C [J].

Baird, DT ;

Webb, R ;

Campbell, BK ;

Harkness, LM ;

Gosden, RG .

ENDOCRINOLOGY, 1999, 140 (01) :462-471

[3]

CANDY CJ, 1995, HUM REPROD, V10, P2334

[4]

GAGNON Y, 1989, CANCER, V64, P892, DOI 10.1002/1097-0142(19890815)64:4<892::AID-CNCR2820640422>3.0.CO

[5]

2-C

[6] RESTORATION OF FERTILITY TO OOPHORECTOMIZED SHEEP BY OVARIAN AUTOGRAFTS STORED AT -196-DEGREES-C [J].

GOSDEN, RG ;

BAIRD, DT ;

WADE, JC ;

WEBB, R .

HUMAN REPRODUCTION, 1994, 9 (04) :597-603

[7]

GOSDEN RG, 1994, J REPROD FERTIL, V101, P619, DOI 10.1530/jrf.0.1010619

[8] Ovarian tissue harvested from lymphoma patients to preserve fertility may be safe for autotransplantation [J].

Kim, SS ;

Radford, J ;

Harris, M ;

Varley, J ;

Rutherford, AJ ;

Lieberman, B ;

Shalet, S ;

Gosden, R .

HUMAN REPRODUCTION, 2001, 16 (10) :2056-2060

[9] Follicular development, ovulation, and corpus luteum formation in cryopreserved human ovarian tissue after xenotransplantation [J].

Kim, SS ;

Soules, MR ;

Battaglia, DE .

FERTILITY AND STERILITY, 2002, 78 (01) :77-82

[10] The future of human ovarian cryopreservation and transplantation: fertility and beyond [J].

Kim, SS ;

Battaglia, DE ;

Soules, MR .

FERTILITY AND STERILITY, 2001, 75 (06) :1049-1056

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