Oxygen uptake and cardiac performance in obese and normal subjects during exercise

被引:82
作者
Salvadori, A
Fanari, P
Fontana, M
Buontempi, L
Saezza, A
Baudo, S
Miserocchi, G
Longhini, E
机构
[1] Ist Auxol Italiano Piancavallo, Div Med Riabilitat, I-28921 Verbania, Italy
[2] Univ Milan, Ist Fisiol Umana 1, Milan, Italy
[3] Osped Citta Sesto San Giovanni, Div Med D&G Campari, Milan, Italy
关键词
oxygen uptake; obesity; exercise testing; cardiac output;
D O I
10.1159/000029333
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Work capacity and cardiopulmonary performance were studied in a group of 11 young obese subjects (BMI 39.9 kg/m(2)) and a group of 10 young normal subjects (BMI 22 kg/m(2)). First of all they underwent an incremental cycle ergometer test up to exhaustion. Subsequently, every subject of the two groups performed a constant work rate test at different work loads to estimate cardiac output ((Q) over dot) below anaerobic threshold (AT) by a 20-second CO2 rebreathing method. Obese subjects had a significantly lower AT (79 vs. 109 W). The ratio between oxygen uptake and heart rate ((V) over dot O-2/HR) (O-2 pulse) was higher in the obese group; nevertheless, this variable became significantly lower if we took into consideration the ratio between O-2 pulse and kilogram fat-free body mass or kilogram body weight. Both these observations suggest that their reduced work tolerance is linked with a reduced oxygen supply to the muscles in activity. (Q) over dot increased in similar ways in obese and normal subjects at the preset work rates. The ratio (Q) over dot/body surface (cardiac index; Cl) that we considered in order to try to minimize the differences in body sizes between the two groups, increased less in response to increasing work rates in our obese subjects than in normal subjects. As a whole, these data appear to be in line with a relatively less efficient cardiac performance during progressive work rates in obese subjects.
引用
收藏
页码:25 / 33
页数:9
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