tRNA mimics

被引：50

作者：

Giegé, R ^{[1
]}

Frugier, M ^{[1
]}

Rudinger, J ^{[1
]}

机构：

[1] CNRS, Inst Biol Mol & Cellulaire, UPR 9002, F-67084 Strasbourg, France

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1998年 / 8卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(98)80060-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mimics recapitulating the structural features of tRNAs are involved in biological processes other than ribosome-dependent protein synthesis. A knowledge of the rules underlying the architecture and function of tRNAs allows the design of non-natural mimics. The study of these mimics sheds light upon links between replication, translation and metabolic pathways, leads to biotechnological applications, and provides experimental and conceptual tools for the exploration of primordial evolutionary processes.

引用

页码：286 / 293

页数：8

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