Limonoids from Swietenia humilis and Guarea grandiflora (Meliaceae)

被引：46

作者：

Jimenez, A

Villarreal, C

Toscano, RA

Cook, M

Arnason, JT ^{[1
]}

Bye, R

Mata, R

机构：

[1] Fac Quim, Dept Farm, Mexico City 04510, DF, Mexico

[2] Inst Quim, Unidad Plantas Med, Mexico City 04510, DF, Mexico

[3] Inst Quim, Lab Rayos X, Mexico City 04510, DF, Mexico

[4] Univ Ottawa, Dept Biol, Ottawa, ON K1N 6N5, Canada

[5] Univ Nacl Autonoma Mexico, Inst Biol, Mexico City 04510, DF, Mexico

来源：

PHYTOCHEMISTRY | 1998年 / 49卷 / 07期

基金：

加拿大自然科学与工程研究理事会;

关键词：

Swietenia humilis; Guarea grandiflora; Meliaceae; limonoids; humilinolides A-F; humilin B; swietenin C; methyl-2-hydroxy-3 beta-isobutyroxy-1-oxomeliac-8(30)-enate; methyl-2-hydroxy-3 beta-tigloyloxy-1-oxomelic-8(30)-enate; swietemahonin C; 21; alpha-acetylmelianone; melianone; melianodiol; gedunin; 7-deacetaxy-7-oxogedunin; 6-alpha-acetoxygedunin; insecticides; European corn borer; Ostrinia nubilalis;

D O I：

10.1016/S0031-9422(98)00364-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new limonoids, humilinolides E and F, were isolated from the seeds of Swietenia humilis Zucc. (Meliaceae). In addition, the known compounds humilinolides A-D, humilin B, swietenin C, methyl-2-hydroxy-3-beta-isobutyroxy- l-oxomeliac-8 (30)-enate, methyl-2-hydroxy-3-beta-tigloyloxy- 1-oxomeliac-8 (30)-enate and swietemahonin C were isolated for biological evaluation with swietenin and swietemahonin C reported for the first time from this species. From the seeds of Guarea grandiflora A.D.C. (Meliaceae) three protolimonoids, namely 21-alpha-acetylmelianone, melianone and melianodiol, and three limonoids, gedunin, 7-deacetoxy-7-oxogedunin and 6-alpha-acetoxygedunin, were obtained. The isolated compounds were identified by spectroscopic methods. Some of the limonoids and protolimonoids were evaluated for their effects on the European corn borer, Ostrinia nubilalis, in comparison with toosendanin a commercial insecticide derived from Melia azederach. (C) 1998 Elsevier Science Ltd. All rights reserved

引用

页码：1981 / 1988

页数：8

共 18 条

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