Evaluation of the fully automated Bactec MGIT 960 system for the susceptibility testing of Mycobacterium tuberculosis to first-line drugs:: a multicenter study

被引：27

作者：

Kontos, F

Maniati, M

Costopoulos, C

Gitti, Z

Nicolaou, S

Petinaki, E

Anagnostou, S

Tselentis, I

Maniatis, AN

机构：

[1] Univ Hosp Larissa, Med Sch, Dept Microbiol, Larisa, Greece

[2] Athens Chest Dis Hosp, Microbiol Lab, Natl Mycobacterium Ref Unit, Athens, Greece

[3] Univ Hosp Crete, Dept Clin Bacteriol Parasitol Zoonoses & Geog Med, Iraklion, Greece

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2004年 / 56卷 / 02期

关键词：

Mycobacterium tuberculosis; Bactec MGIT 960 system; susceptibility testing;

D O I：

10.1016/j.mimet.2003.10.015

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The accuracy of the Bactec MGIT 960 system for susceptibility testing of 177 clinical isolates of Mycobacterium tuberculosis to first line drugs (isoniazid, rifampicin, ethambutol and streptomycin) was compared with the agar reference method. The sensitivity, the ability to detect resistance, of the MGIT system was 100%, while the specificity, the ability to detect susceptibility, ranged from 98.6% to 100% for all drugs tested. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：291 / 294

页数：4

共 11 条

[1] Susceptibility testing with the manual mycobacteria growth indicator tube (MGIT) and the MGIT 960 system provides rapid and reliable verification of multidrug-resistant tuberculosis [J].