A stacked pyrazolo[3,4-d]pyrimidine-based flexible molecule:: the effect on stacking of an ethyl group in comparison with a methyl group

被引：20

作者：

Avasthi, K

Aswal, S

Maulik, PR ^{[1
]}

机构：

[1] Cent Drug Res Inst, Mol & Struct Biol Div, Lucknow 226001, Uttar Pradesh, India

[2] Cent Drug Res Inst, Div Med Chem, Lucknow 226001, Uttar Pradesh, India

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 2001年 / 57卷 / 11期

关键词：

Intramolecular stackings;

D O I：

10.1107/S0108270101013518

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the crystal structure of 1,1'-(1,3-propanediyl)bis(5-ethyl-6-methylthio-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one), C19H24N8O2S2, the pairs of pyrazolo[3,4-d]pyrimidine rings of the molecule stack between the heterocyclic rings, due to intramolecular pi-pi interactions. The substituted ethyl and methyl groups are comparable as far as intramolecular stacking is concerned.

引用

页码：1324 / 1325

页数：2

共 16 条

[1]

AVASTHI K, 1995, INDIAN J CHEM B, V34, P944

[2]

Avasthi K, 1998, INDIAN J CHEM B, V37, P754

[3]

AVASTHI K, 2001, UNPUB

[4] 1,3-BIS[4,6-BIS(METHYLTHIO)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PROPANE [J].