Chemotaxonomic study of medicinal Taxus species with fingerprint and multivariate analysis

被引：27

作者：

Ge, Guang-Bo ^{[1
,2
]}

Zhang, Yan-Yan ^{[1
,2
]}

Hao, Da-Cheng ^{[1
,2
]}

Hu, Ying ^{[1
,2
]}

Luan, Hong-Wei ^{[1
,2
]}

Liu, Xing-Bao ^{[1
]}

He, Yu-Qi ^{[3
]}

Wang, Zheng-Tao ^{[3
]}

Yang, Ling ^{[1
]}

机构：

[1] Chinese Acad Sci, Lab Pharmaceut Resource Discovery, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

[2] Grad Univ Chinese Acad Sci, Beijing, Peoples R China

[3] Shanghai Univ Tradit Chinese Med, Key Lab Standardizat Chinese Med, Minist Educ, Shanghai, Peoples R China

来源：

PLANTA MEDICA | 2008年 / 74卷 / 07期

关键词：

Taxus; Taxaceae; chemotaxonomy; fingerprinting; multivariate analysis; taxanes;

D O I：

10.1055/s-2008-1074531

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Species delimitation in Taxus has been controversial and it is very difficult to distinguish yew materials by their morphological characters. In this paper, a valid HPLC fingerprinting method coupled with multivariate analysis was used to define a framework for Taxus species identification and classification. Fingerprint-based similarity was employed for a chemotaxonomic study by hierarchical clustering analysis (HCA) and principal component analysis (PCA). Based on the PCA loadings, twelve chemical constituents were selected as chemotaxonomic markers which can be used to establish a more practical classification. Finally, eight studied species could be divided into six well-supported groups and most samples can be assigned to the correct species. Additionally, twelve markers were tentatively identified by LC/MS.

引用

页码：773 / 779

页数：7

共 28 条

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