The evaluation of antihypertensive therapy using 24-h ambulatory monitoring technology

被引：4

作者：

White, WB ^{[1
]}

机构：

[1] Univ Connecticut, Ctr Hlth, Sch Med, Sect Hypertens & Clin Pharmacol, Farmington, CT 06030 USA

来源：

BLOOD PRESSURE MONITORING | 2000年 / 5卷

关键词：

ambulatory blood pressure; antihypertensive drugs; blood pressure measurement; clinical trials; placebo effects;

D O I：

10.1097/00126097-200010002-00004

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Several specific features of ambulatory monitoring of the blood pressure have made it important in clinical trials that assess antihypertensive drug therapy. These include the removal of observer bias, improved short-term and long-term blood pressure reproducibility compared with clinic readings, elimination of the 'white-coat' effect during patient selection and the ability to assess the effects of long-acting once daily therapies on diurnal and nocturnal blood pressure. In this article, an overview of the utility of ambulatory brood pressure monitoring in clinical trials is provided, with specific examples that use data from recent studies of the newer compounds that block the renin-angiotensin system. Blood Press Monit 5 (suppl 2):S13-S17 (C) 2000 Lippincott Williams & Wilkins.

引用

页码：S13 / S17

页数：5

共 32 条

[1]

BRUCE NG, 1988, J HYPERTENS, V6, P375

[2]

CONWAY J, 1988, J HYPERTENS, V6, P111

[3] LACK OF CORRELATION BETWEEN CLINIC AND 24 HOUR AMBULATORY BLOOD-PRESSURE IN SUBJECTS PARTICIPATING IN A THERAPEUTIC DRUG TRIAL [J].

GRADMAN, AH ;

PANGAN, P ;

GERMAIN, M .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 1989, 42 (11) :1049-1054

[4] MANAGEMENT OF HYPERTENSION AFTER AMBULATORY BLOOD-PRESSURE MONITORING [J].

GRIN, JM ;

MCCABE, EJ ;

WHITE, WB .

ANNALS OF INTERNAL MEDICINE, 1993, 118 (11) :833-837

[5] THE REPRODUCIBILITY OF AVERAGE AMBULATORY, HOME, AND CLINIC PRESSURES [J].

JAMES, GD ;

PICKERING, TG ;

YEE, LS ;

HARSHFIELD, GA ;

RIVA, S ;

LARAGH, JH .

HYPERTENSION, 1988, 11 (06) :545-549

[6] Cardiovascular outcome in white-coat versus sustained mild hypertension - A 10-year follow-up study [J].

Khattar, RS ;

Senior, R ;

Lahiri, A .

CIRCULATION, 1998, 98 (18) :1892-1897

[7] AMBULATORY BLOOD-PRESSURE MONITORING IN A NONACADEMIC SETTING - EFFECTS OF AGE AND SEX [J].

KHOURY, S ;

YAROWS, SA ;

OBRIEN, TK ;

SOWERS, JR .

AMERICAN JOURNAL OF HYPERTENSION, 1992, 5 (09) :616-623

[8]

LACOURCIERE Y, 1998, BLOOD PRESS MONIT, V2, P295

[9] ABPM comparison of the antihypertensive profiles of the selective angiotensin II receptor antagonists telmisartan and losartan in patients with mild-to-moderate hypertension [J].

Maillon, JM ;

Siche, JP ;

Lacourcière, Y .

JOURNAL OF HUMAN HYPERTENSION, 1999, 13 (10) :657-664

[10] LIMITED REPRODUCIBILITY OF HOURLY BLOOD-PRESSURE VALUES OBTAINED BY AMBULATORY BLOOD-PRESSURE MONITORING - IMPLICATIONS FOR STUDIES ON ANTIHYPERTENSIVE DRUGS [J].

MANCIA, G ;

OMBONI, S ;

PARATI, G ;

TRAZZI, S ;

MUTTI, E .

JOURNAL OF HYPERTENSION, 1992, 10 (12) :1531-1535

← 1 2 3 4 →