Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria

被引：126

作者：

Barnard, Anne M. L. ^{[1
]}

Bowden, Steven D. ^{[1
]}

Burr, Tom ^{[1
]}

Coulthurst, Sarah J. ^{[1
]}

Monson, Rita E. ^{[1
]}

Salmond, George P. C. ^{[1
]}

机构：

[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1QW, England

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 2007年 / 362卷 / 1483期

关键词：

Erwinia; quorum sensing; N-acylhomoserine lactone; carbapenem antibiotic; virulence; phytopathogenicity;

D O I：

10.1098/rstb.2007.2042

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Quorum sensing describes the ability of bacteria to sense their population density and respond by modulating gene expression. In the plant soft-rotting bacteria, such as Erwinia, an arsenal of plant cell wall-degrading enzymes is produced in a cell density-dependent manner, which causes maceration of plant tissue. However, quorum sensing is central not only to controlling the production of such destructive enzymes, but also to the control of a number of other virulence determinants and secondary metabolites. Erwinia synthesizes both N-acylhomoserine lactone (AHL) and autoinducer-2 types of quorum sensing signal, which both play a role in regulating gene expression in the phytopathogen. We review the models for AHL-based regulation of carbapenem antibiotic production in Erwinia. We also discuss the importance of quorum sensing in the production and secretion of virulence determinants by Erwinia, and its interplay with other regulatory systems.

引用

页码：1165 / 1183

页数：19

共 137 条

[1] Type III secretion system effector proteins: Double agents in bacterial disease and plant defense [J].

Alfano, JR ;

Collmer, A .

ANNUAL REVIEW OF PHYTOPATHOLOGY, 2004, 42 :385-414

[2] Role of RpoS in virulence and stress tolerance of the plant pathogen Erwinia carotovora subsp carotovora [J].

Andersson, RA ;

Koiv, V ;

Norman-Setterblad, C ;

Pirhonen, M .

MICROBIOLOGY-SGM, 1999, 145 :3547-3556

[3] Quorum sensing in the plant pathogen Erwinia carotovora subsp carotovora:: The role of expREcc [J].

Andersson, RA ;

Eriksson, ARB ;

Heikinheimo, R ;

Mäe, A ;

Pirhonen, M ;

Koiv, V ;

Hyytiäinen, H ;

Tuikkala, A ;

Palva, ET .

MOLECULAR PLANT-MICROBE INTERACTIONS, 2000, 13 (04) :384-393

[4] Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics [J].

Arevalo-Ferro, C ;

Hentzer, M ;

Reil, G ;

Görg, A ;

Kjelleberg, S ;

Givskov, M ;

Riedel, K ;

Eberl, L .

ENVIRONMENTAL MICROBIOLOGY, 2003, 5 (12) :1350-1369

[5] Synthesis of autoinducer 2 by the Lyme disease spirochete, Borrelia burgdorferi [J].

Babb, K ;

von Lackum, K ;

Wattier, RL ;

Riley, SP ;

Stevenson, B .

JOURNAL OF BACTERIOLOGY, 2005, 187 (09) :3079-3087

[6] A GENERAL ROLE FOR THE LUX AUTOINDUCER IN BACTERIAL-CELL SIGNALING - CONTROL OF ANTIBIOTIC BIOSYNTHESIS IN ERWINIA [J].

BAINTON, NJ ;

BYCROFT, BW ;

CHHABRA, SR ;

STEAD, P ;

GLEDHILL, L ;

HILL, PJ ;

REES, CED ;

WINSON, MK ;

SALMOND, GPC ;

STEWART, GSAB ;

WILLIAMS, P .

GENE, 1992, 116 (01) :87-91

[7] N-(3-OXOHEXANOYL)-L-HOMOSERINE LACTONE REGULATES CARBAPENEM ANTIBIOTIC PRODUCTION IN ERWINIA-CAROTOVORA [J].

BAINTON, NJ ;

STEAD, P ;

CHHABRA, SR ;

BYCROFT, BW ;

SALMOND, GPC ;

STEWART, GSAB ;

WILLIAMS, P .

BIOCHEMICAL JOURNAL, 1992, 288 :997-1004

[8] CsrA regulates glycogen biosynthesis by preventing translation of glgC in Escherichia coli [J].

Baker, CS ;

Morozov, I ;

Suzuki, K ;

Romeo, T ;

Babitzke, P .

MOLECULAR MICROBIOLOGY, 2002, 44 (06) :1599-1610

[9] EXTRACELLULAR ENZYMES AND PATHOGENESIS OF SOFT-ROT ERWINIA [J].

BARRAS, F ;

VANGIJSEGEM, F ;

CHATTERJEE, AK .

ANNUAL REVIEW OF PHYTOPATHOLOGY, 1994, 32 :201-234

[10] A single gene that promotes interaction of a phytopathogenic bacterium with its insect vector, Drosophila melanogaster [J].

Basset, A ;

Tzou, P ;

Lemaitre, B ;

Boccard, F .

EMBO REPORTS, 2003, 4 (02) :205-209

← 1 2 3 4 5 6 7 8 9 10 →