A comparison of experience-dependent plasticity in the visual and somatosensory systems

被引：173

作者：

Fox, K

Wong, ROL

机构：

[1] Cardiff Univ, Cardiff Business Sch, Cardiff CF10 3US, S Glam, Wales

[2] Washington Univ, Sch Med, Dept Anat & Neurobiol, St Louis, MO 63110 USA

来源：

NEURON | 2005年 / 48卷 / 03期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/j.neuron.2005.10.013

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In the visual and somatosensory systems, maturation of neuronal circuits continues for days to weeks after sensory stimulation occurs. Deprivation of sensory input at various stages of development can induce physiological, and often structural, changes that modify the circuitry of these sensory systems. Recent studies also reveal a surprising degree of plasticity in the mature visual and somatosensory pathways. Here, we compare and contrast the effects of sensory experience on the connectivity and function of these pathways and discuss what is known to date concerning the structural, physiological, and molecular mechanisms underlying their plasticity.

引用

页码：465 / 477

页数：13

共 99 条

[1] Long-term depression induced by sensory deprivation during cortical map plasticity in vivo [J].