Enhanced antioxidant bioactivity of Salvia miltiorrhiza (Danshen) products prepared using nanotechnology

被引：29

作者：

Liu, Je-Ruei ^{[2
,3
]}

Chen, Guo-Feng ^{[1
]}

Shih, Hui-Nung ^{[1
]}

Kuo, Ping-Chung ^{[1
]}

机构：

[1] Natl Formosa Univ, Dept Biotechnol, Huwei Town 632, Yunlin, Taiwan

[2] Natl Taiwan Univ, Dept Anim Sci & Technol, Taipei, Taiwan

[3] Natl Taiwan Univ, Inst Biotechnol, Taipei, Taiwan

来源：

PHYTOMEDICINE | 2008年 / 15卷 / 1-2期

关键词：

traditional Chinese medicine; antioxidant activity; HPLC; salvianolic acid B;

D O I：

10.1016/j.phymed.2007.11.012

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The traditional Chinese medicine, Salvia miltiorrhiza (Danshen), promotes blood circulation and relieves blood stasis, also demonstrating good antioxidant activity. In the present study, therefore, the antioxidant activities of medicinal plant materials prepared using nanotechnology or traditional grinding methods were compared using three biological assays. It was found that the nanotechnology preparation had stronger antioxidant bioactivities. Complementary quantitative analysis of four active constituents, salvianolic acid B, cryptotanshinone, tanshinone I and tanshinone IIA, by HPLC revealed only marked differences for salvianolic acid B. The results indicate that the polar active constituent in the nanotechnology samples was released faster compared to the traditionally powdered samples. (C) 2007 Elsevier GmbH. All rights reserved.

引用

页码：23 / 30

页数：8

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