RB kinases and RB-binding proteins: New points of view

被引：222

作者：

Taya, Y

机构：

[1] National Cancer Center, Research Institute, Chuo-ku, Tokyo 104

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1997年 / 22卷 / 01期

关键词：

RETINOBLASTOMA GENE-PRODUCT; CELL-CYCLE INHIBITION; TRANSCRIPTIONAL REPRESSION; NEGATIVE REGULATOR; MOLECULAR-CLONING; PHASE-TRANSITION; G(1); IDENTIFICATION; EXPRESSION; COMPLEX;

D O I：

10.1016/S0968-0004(96)10070-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The retinoblastoma protein (RE) binds to a variety of cellular proteins and suppresses cellular growth. Such interactions are regulated by phosphorylation during the cell cycle by several cyclin-dependent kinases, known as RE kinases. Clues to the specific physiological roles of different RE kinases have been obtained. Moreover, interesting functions of the RE protein, other than control of E2F activity have been found.

引用

收藏

页码：14 / 17

页数：4

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