Autophagy and Myocardial Ischemia

被引：51

作者：

Du, Jie ^{[1
]}

Li, Yulin ^{[1
]}

Zhao, Wei ^{[1
]}

机构：

[1] Capital Med Univ, Beijing Anzhen Hosp, Beijing, Peoples R China

来源：

AUTOPHAGY: BIOLOGY AND DISEASES: CLINICAL SCIENCE | 2020年 / 1207卷

关键词：

Autophagy; Myocardial ischemia; Ischemia/reperfusion; Energy metabolism; Reactive oxygen species;

D O I：

10.1007/978-981-15-4272-5_15

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

100103 [病原生物学]; 100218 [急诊医学];

摘要：

Myocardial ischemia and reperfusion cause injury to the heart in myocardial ischemic disease. Both processes increase autophagy. In this chapter, we will provide an overview of the autophagic mechanism caused by myocardial ischemia/reperfusion injury and the role of autophagy in myocardial ischemia/reperfusion injury.

引用

收藏

页码：217 / 222

页数：6

相关论文

共 7 条

[1]

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks [J].

Alers, Sebastian ;

Loeffler, Antje S. ;

Wesselborg, Sebastian ;

Stork, Bjoern .

MOLECULAR AND CELLULAR BIOLOGY, 2012, 32 (01) :2-11

[2]

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3 [J].

Azad, Meghan B. ;

Chen, Yongqiang ;

Henson, Elizabeth S. ;

Cizeau, Jeannick ;

McMillan-Ward, Eileen ;

Israels, Sara J. ;

Gibson, Spencer B. .

AUTOPHAGY, 2008, 4 (02) :195-204

[3]

DECKER RS, 1980, AM J PATHOL, V98, P425

[4]

Is autophagy a double-edged sword for the heart? [J].

Gurusamy, N. ;

Das, D. K. .

ACTA PHYSIOLOGICA HUNGARICA, 2009, 96 (03) :267-276

[5]

Stimulation of mitochondrial biogenesis and autophagy by lipopolysaccharide in the neonatal rat cardiomyocyte protects against programmed cell death [J].

Hickson-Bick, Diane L. M. ;

Jones, Chad ;

Buja, L. Maximilian .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2008, 44 (02) :411-418

[6]

Distinct roles of autophagy in the heart during ischemia and reperfusion - Roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy [J].

Matsui, Yutaka ;

Takagi, Hiromitsu ;

Qu, Xueping ;

Abdellatif, Maha ;

Sakoda, Hideyuki ;

Asano, Tomoichiro ;

Levine, Beth ;

Sadoshima, Junichi .

CIRCULATION RESEARCH, 2007, 100 (06) :914-922

[7]

Sybers H D, 1976, Recent Adv Stud Cardiac Struct Metab, V12, P453