Supramolecular assemblies of DNA with neutral nucleoside amphiphiles

被引：26

作者：

Barthelemy, P

Prata, CAH

Filocamo, SF

Immoos, CE

Maynor, BW

Hashmi, SAN

Lee, SJ

Grinstaff, MW ^{[1
]}

机构：

[1] Boston Univ, Dept Chem, Boston, MA 02215 USA

[2] Boston Univ, Dept Biomed Engn, Boston, MA 02215 USA

[3] Fac Sci Avignon, F-84000 Avignon, France

[4] USA, Res Off, Res Triangle Pk, NC 27709 USA

[5] Calif Polytech State Univ San Luis Obispo, Dept Chem, San Luis Obispo, CA 93407 USA

[6] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

[7] Duke Univ, Dept Chem, Durham, NC 27708 USA

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 10期

关键词：

D O I：

10.1039/b412670j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A neutral uridine-based amphiphile is described which condenses plasmid DNA. AFM studies show that the three distinct structural components of the amphiphile (i.e, nucleobase, alkyl chains, and poly( ethylene glycol)) are required for the formation of DNA - amphiphile supramolecular assemblies on a mica surface.

引用

页码：1261 / 1263

页数：3

共 30 条

[1]

[Anonymous], 1992, INTERMOLECULAR SURFA

[2] Artificial viruses and their application to gene delivery. size-controlled gene coating with glycocluster nanoparticles [J].