An expedient one-pot synthesis for protected 2-thia-5-azabicyclo[2.2.1]heptan-3-ones. Versatile intermediates in the synthesis of carbapenem sidechains.

被引：8

作者：

Brands, KMJ

Marchesini, G

Williams, JM

Dolling, UH

Reider, PJ

机构：

[1] Merck Research Laboratories, Department of Process Research, Rahway, NJ 07065

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 17期

关键词：

D O I：

10.1016/0040-4039(96)00447-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and high yielding one-pot process for the preparation of protected 2-thia-5-azabicyclo-[2.2.1]heptan-3-ones from 4-hydroxyproline and their use in the synthesis of carbapenem sidechains is described. (C) 1996 Elsevier Science Ltd

引用

页码：2919 / 2922

页数：4

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