Letter to the Editor:: 1H, 15N and 13C chemical shift assignments of the Pleckstrin Homology domain of the Human Protein Kinase B (PKB/Akt)

被引:3
作者
Auguin, D
Barthe, P
Augé-Sénégas, MT
Hoh, F
Noguchi, M
Roumestand, C
机构
[1] Fac Pharm Montpellier, Ctr Biochim Struct, UMR 5548, CNRS UM1,UMR 554,INSERM UM1, F-34093 Montpellier 5, France
[2] Hokkaido Univ, Div Canc Biol, Inst Med Genet, Kita Ku, Sapporo, Hokkaido 0600815, Japan
关键词
Akt; apoptosis; NMR assignments; PH domain; PKB; proliferation;
D O I
10.1023/A:1025490109384
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:287 / 288
页数:2
相关论文
共 9 条
[1]   A modeled hydrophobic domain on the TCL1 oncoprotein mediates association with AKT at the cytoplasmic membrane [J].
French, SW ;
Shen, RR ;
Koh, PJ ;
Malone, CS ;
Mallick, P ;
Teitell, MA .
BIOCHEMISTRY, 2002, 41 (20) :6376-6382
[2]   Crystal structure of p14TCL1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel β-barrel topology [J].
Hoh, F ;
Yang, YS ;
Guignard, L ;
Padilla, A ;
Stern, MH ;
Lhoste, JM ;
van Tilbeurgh, H .
STRUCTURE, 1998, 6 (02) :147-155
[3]   Identification of Akt association and oligomerization domains of the Akt kinase coactivator TCL1 [J].
Künstle, G ;
Laine, J ;
Pierron, G ;
Kagami, S ;
Nakajima, H ;
Hoh, F ;
Roumestand, C ;
Stern, MH ;
Noguchi, M .
MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (05) :1513-1525
[4]   The protooncogene TCL1 is an Akt kinase coactivator [J].
Laine, J ;
Künstle, G ;
Obata, T ;
Sha, M ;
Noguchi, M .
MOLECULAR CELL, 2000, 6 (02) :395-407
[5]   The protein kinase B/Akt signalling pathway in human malignancy [J].
Nicholson, KM ;
Anderson, NG .
CELLULAR SIGNALLING, 2002, 14 (05) :381-395
[6]  
Pons JL, 1996, J BIOMOL NMR, V8, P445, DOI 10.1007/BF00228146
[7]  
STALL SP, 1987, P NATL ACAD SCI USA, V84, P5034
[8]   High-resolution structure of the pleckstrin homology domain of protein kinase B/Akt bound to phosphatidylinositol (3,4,5)-trisphosphate [J].
Thomas, CC ;
Deak, M ;
Alessi, DR ;
van Aalten, DMF .
CURRENT BIOLOGY, 2002, 12 (14) :1256-1262
[9]   Solution structure of the recombinant human oncoprotein p13MTCP1 [J].
Yang, YS ;
Guignard, L ;
Padilla, A ;
Hoh, F ;
Strub, MP ;
Stern, MH ;
Lhoste, JM ;
Roumestand, C .
JOURNAL OF BIOMOLECULAR NMR, 1998, 11 (03) :337-354