An Efficient Three-Component Synthesis of Benzimidazo[1,2-a]-quinoline-6-carbonitriles

被引：15

作者：

Adib, Mehdi ^{[1
]}

Zainali, Mohsen ^{[1
]}

Kim, Il ^{[2
]}

机构：

[1] Univ Tehran, Sch Chem, Coll Sci, POB 14155-6455, Tehran, Iran

[2] Pusan Natl Univ, Dept Polymer Sci & Engn, PLUS Ctr Adv Chem Technol BK21, Pusan 609735, South Korea

来源：

SYNLETT | 2016年 / 27卷 / 12期

关键词：

benzene-1; 2-diamines; cyclohexane-1; 3-diones; arylidenemalononitriles; benzimidazo[1; 2-a]quinoline-6-carbonitriles; multicomponent reactions; ANTITUMOR EVALUATION; DERIVATIVES;

D O I：

10.1055/s-0035-1561939

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

An efficient three-component synthesis of benzimidazo[1,2-a]quinoline-6-carbonitriles is described. Condensation reaction of a benzene-1,2-diamine and a cyclohexane-1,3-dione gave an enamine intermediate, which on treatment with an arylidenemalononitrile in water-ethanol (1:1) afforded the title compounds in good to excellent yields.

引用

收藏

页码：1844 / 1847

页数：4

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