Why do regulators of apoptosis look like bacterial toxins?

[1] Life-or-death decisions by the Bcl-2 protein family [J]. TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (01) : 61 - 66

[2] Penetration of protein toxins into cells [J]. CURRENT OPINION IN CELL BIOLOGY, 2000, 12 (04) : 407 - 413

[3] BCL-2 family members and the mitochondria in apoptosis [J]. GENES & DEVELOPMENT, 1999, 13 (15) : 1899 - 1911

[4] The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability [J]. CELL DEATH AND DIFFERENTIATION, 2000, 7 (12) : 1182 - 1191

[5] The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis [J]. SCIENCE, 1997, 275 (5303) : 1132 - 1136

[6] Lakey JH, 2001, CURR TOP MICROBIOL, V257, P131

[7] GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity [J]. EMBO JOURNAL, 1996, 15 (04) : 725 - 734

[8] Receptor-mediated uptake of an extracellular Bcl-xL fusion protein inhibits apoptosis [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (17) : 9563 - 9567

[9] MEMBRANE TRANSLOCATION OF DIPHTHERIA-TOXIN CARRYING PASSENGER PROTEIN DOMAINS [J]. INFECTION AND IMMUNITY, 1992, 60 (08) : 3296 - 3302

[10] X-ray and NMR structure of human Bcl-x(L), an inhibitor of programmed cell death [J]. NATURE, 1996, 381 (6580) : 335 - 341

[1] Life-or-death decisions by the Bcl-2 protein family [J]. TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (01) : 61 - 66

[2] Penetration of protein toxins into cells [J]. CURRENT OPINION IN CELL BIOLOGY, 2000, 12 (04) : 407 - 413

[3] BCL-2 family members and the mitochondria in apoptosis [J]. GENES & DEVELOPMENT, 1999, 13 (15) : 1899 - 1911

[4] The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability [J]. CELL DEATH AND DIFFERENTIATION, 2000, 7 (12) : 1182 - 1191

[5] The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis [J]. SCIENCE, 1997, 275 (5303) : 1132 - 1136

[6] Lakey JH, 2001, CURR TOP MICROBIOL, V257, P131

[7] GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity [J]. EMBO JOURNAL, 1996, 15 (04) : 725 - 734

[8] Receptor-mediated uptake of an extracellular Bcl-xL fusion protein inhibits apoptosis [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (17) : 9563 - 9567

[9] MEMBRANE TRANSLOCATION OF DIPHTHERIA-TOXIN CARRYING PASSENGER PROTEIN DOMAINS [J]. INFECTION AND IMMUNITY, 1992, 60 (08) : 3296 - 3302

[10] X-ray and NMR structure of human Bcl-x(L), an inhibitor of programmed cell death [J]. NATURE, 1996, 381 (6580) : 335 - 341