Pouch-anal cancer after restorative proctocolectomy for familial adenomatous polyposis

被引：59

作者：

vonHerbay, A ^{[1
]}

Stern, J ^{[1
]}

Herfarth, C ^{[1
]}

机构：

[1] UNIV HEIDELBERG,DEPT SURG,D-69120 HEIDELBERG,GERMANY

来源：

AMERICAN JOURNAL OF SURGICAL PATHOLOGY | 1996年 / 20卷 / 08期

关键词：

familial adenomatous polyposis; cancer; restorative proctocolectomy; ileal pouch; mucosectomy; pathology; surgery;

D O I：

10.1097/00000478-199608000-00008

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Familial adenomatous polyposis (FAP) and idiopathic ulcerative colitis are both mucosal diseases that bear a significant risk of developing colorectal cancer. As a consequence, their surgical treatment is currently widely per formed by restorative proctocolectomy with pelvic ileal pouch-anal anastomosis (IPAA). Herein we report a new case of cancer after IPAA that developed in a 33-year-old woman with FAP. Pouch-anal cancer was diagnosed 8 years after restorative proctocolectomy, including anorectal mucosectomy, for FAP with manifest cancer in the sigmoid colon. This case observation reemphasizes that the risk of cancer for FAP patients persists as long as any rectal mucosa remains after IPAA surgery.

引用

页码：995 / 999

页数：5

共 23 条

[1] THE HISTOLOGICAL PATTERN AND PATHOLOGICAL INVOLVEMENT OF THE ANAL TRANSITION ZONE IN PATIENTS WITH ULCERATIVE-COLITIS [J].

AMBROZE, WL ;

PEMBERTON, JH ;

DOZOIS, RR ;

CARPENTER, HA ;

OROURKE, JS ;

ILSTRUP, DM .

GASTROENTEROLOGY, 1993, 104 (02) :514-518

[2]

BESS MA, 1980, ARCH SURG-CHICAGO, V115, P460

[3]

BUHR HJ, 1993, CHIRURG, V64, P601

[4]

COHEN Z, 1991, DIS COLON RECTUM, V32, P283

[5] RECTAL-CANCER RISK IN PATIENTS TREATED FOR FAMILIAL ADENOMATOUS POLYPOSIS [J].

DECOSSE, JJ ;

BULOW, S ;

NEALE, K ;

JARVINEN, H ;

ALM, T ;

HULTCRANTZ, R ;

MOESGAARD, F ;

COSTELLO, C ;

MACRAE, FA ;

WATTS, C ;

BERK, T ;

COHEN, Z ;

IWAMA, T ;

JAGELMAN, DG ;

MCGANNON, E ;

DECOSSE, JJ ;

THOMSON, JPS ;

ITOH, H ;

BABA, S ;

MUTO, T .

BRITISH JOURNAL OF SURGERY, 1992, 79 (12) :1372-1375

[6]

FENGER C, 1986, AM J SURG PATHOL, V12, P41

[7] FATE OF THE RECTAL MUCOSA AFTER RECTAL MUCOSECTOMY AND ILEOANAL ANASTOMOSIS [J].

HEPPELL, J ;

WEILAND, LH ;

PERRAULT, J ;

PEMBERTON, JH ;

TELANDER, RL ;

BEART, RW .

DISEASES OF THE COLON & RECTUM, 1983, 26 (12) :768-771

[8]

HERFARTH C, 1990, FUNKTIONSERHALTENDE

[9]

JASS JR, 1989, WHO INT HISTOLOGICAL, P41

[10] ANAL-CANAL MUCOSA IN RESTORATIVE PROCTOCOLECTOMY FOR ULCERATIVE-COLITIS [J].

KING, DW ;

LUBOWSKI, DZ ;

COOK, TA .

BRITISH JOURNAL OF SURGERY, 1989, 76 (09) :970-972

← 1 2 3 →