Zr-catalyzed electrophilic carbomagnesation of aryl olefins. Mechanism-based control of Zr-Mg ligand exchange

被引：13

作者：

de Armas, J ^{[1
]}

Hoveyda, AH ^{[1
]}

机构：

[1] Boston Coll, Dept Chem, Merkert Chem Ctr, Chestnut Hill, MA 02467 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 13期

关键词：

D O I：

10.1021/ol0160607

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The first examples of efficient electrophilic Zr-catalyzed carbomagnesations are disclosed, where in contrast to previous catalytic carbomagnesations the alkyl moiety of the electrophile is transferred (vs that of the Grignard reagent), The identity of the Grignard reagent is manipulated so that Zr-Mg exchange is facilitated, leading to the formation of alkylmagnesium halide products.

引用

页码：2097 / 2100

页数：4

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