Total synthesis of (-)-colombiasin A and (-)-elisapterosin B

被引：78

作者：

Harrowven, DC ^{[1
]}

Pascoe, DD ^{[1
]}

Demurtas, D ^{[1
]}

Bourne, HO ^{[1
]}

机构：

[1] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 08期

关键词：

cycloaddition; diterpenes; marine natural products; rearrangement; total synthesis;

D O I：

10.1002/anie.200462268

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Intramolecular cycloaddition reactions are central in the total syntheses of colombiasin A (1) and elisapterosin B (2) described, which use (-)-dihydrocarvone as the starting material. A Moore rearrangement of a vinylcyclobutene is used to initiate the cycloaddition. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1221 / 1222

页数：2

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