Salvinorins D-F, new neoclerodane diterpenoids from Salvia divinorum, and an improved method for the isolation of salvinorin A

被引:75
作者
Munro, TA [1 ]
Rizzacasa, MA [1 ]
机构
[1] Univ Melbourne, Sch Chem, Melbourne, Vic 3010, Australia
来源
JOURNAL OF NATURAL PRODUCTS | 2003年 / 66卷 / 05期
关键词
D O I
10.1021/np0205699
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Three new neoclerodane diterpenoids, salvinorins D-F (4-6), have been isolated from the leaves of Salvia divinorum. The structures were elucidated by chemical and spectroscopic methods, particularly 1D and 2D NMR. A simplified isolation method using chromatography on activated carbon also gave improved yields of the controlled substance salvinorin A (1) and of salvinorin C (3).
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页码:703 / 705
页数:3
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