Acquisition of ischemic tolerance by repetitive transcranial magnetic stimulation in the rat hippocampus

被引：35

作者：

Ogiue-Ikeda, M ^{[1
]}

Kawato, S

Ueno, S

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Biomed Engn, Tokyo, Japan

[2] Univ Tokyo, Grad Sch Arts & Sci, Dept Biophys & Life Sci, Tokyo, Japan

来源：

BRAIN RESEARCH | 2005年 / 1037卷 / 1-2期

关键词：

repetitive transcranial magnetic stimulation (rTMS); hippocampus; ischemic tolerance; long-term potentiation (LTP);

D O I：

10.1016/j.brainres.2004.10.063

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We investigated the acquisition of ischemic tolerance in the rat hippocampus using repetitive transcranial magnetic stimulation (rTMS). Rats received 1000 pulses/day for 7 days, and the field excitatory postsynaptic, potentials were measured in the hippocampal CA1. After slices were exposed to ischemic conditions, long-term potentiation (LTP) was induced. The UP of the stimulated group was enhanced compared with the LTP of the sham control group in each ischemic condition, suggesting that rTMS has the potential to protect hippocampal function from ischemia. (c) 2004 Elsevier B.V. All rights reserved.

引用

页码：7 / 11

页数：5

共 22 条

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