Genetics of common polygenic stroke

被引：26

作者：

Dominiczak, AF ^{[1
]}

McBride, MW ^{[1
]}

机构：

[1] Univ Glasgow, Western Infirm, Div Cardiovasc & Med Sci, BHF Glasgow Cardiovasc Res Ctr, Glasgow G11 6NT, Lanark, Scotland

来源：

NATURE GENETICS | 2003年 / 35卷 / 02期

关键词：

D O I：

10.1038/ng1003-116

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Ischemic stroke is a late-onset, complex polygenic disease, and it has proven difficult to identify its genetic determinants. A new study from Iceland shows that the gene encoding phosphodiesterase 4D is the most likely positional and pathophysiological candidate underlying the stroke susceptibility locus on chromosome 5q12.

引用

页码：116 / 117

页数：3

共 15 条

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