Applications of microarray technology in breast cancer research

被引:60
作者
Cooper, CS [1 ]
机构
[1] Inst Canc Res, Haddow Labs, Sutton SM2 5NG, Surrey, England
关键词
drug discovery; genetic gains and losses; microarrays; microarray design; mutation detection; tumour classification;
D O I
10.1186/bcr291
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Microarrays provide a versatile platform for utilizing information from the Human Genome Project to benefit human health. This article reviews the ways in which microarray technology may be used in breast cancer research. its diverse applications include monitoring chromosome gains and losses, tumour classification, drug discovery and development, DNA resequencing, mutation detection and investigating the mechanism of tumour development.
引用
收藏
页码:158 / 175
页数:18
相关论文
共 98 条
[1]
Afshari CA, 1999, CANCER RES, V59, P4759
[2]
Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array [J].
Ahrendt, SA ;
Halachmi, S ;
Chow, JT ;
Wu, L ;
Halachmi, N ;
Yang, SC ;
Wehage, S ;
Jen, J ;
Sidransky, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (13) :7382-7387
[3]
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats [J].
Aitman, TJ ;
Glazier, AM ;
Wallace, CA ;
Cooper, LD ;
Norsworthy, PJ ;
Wahid, FN ;
Al-Majali, KM ;
Trembling, PM ;
Mann, CJ ;
Shoulders, CC ;
Graf, D ;
St Lezin, E ;
Kurtz, TW ;
Kren, V ;
Pravenec, M ;
Ibrahimi, A ;
Abumrad, NA ;
Stanton, LW ;
Scott, J .
NATURE GENETICS, 1999, 21 (01) :76-83
[4]
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling [J].
Alizadeh, AA ;
Eisen, MB ;
Davis, RE ;
Ma, C ;
Lossos, IS ;
Rosenwald, A ;
Boldrick, JG ;
Sabet, H ;
Tran, T ;
Yu, X ;
Powell, JI ;
Yang, LM ;
Marti, GE ;
Moore, T ;
Hudson, J ;
Lu, LS ;
Lewis, DB ;
Tibshirani, R ;
Sherlock, G ;
Chan, WC ;
Greiner, TC ;
Weisenburger, DD ;
Armitage, JO ;
Warnke, R ;
Levy, R ;
Wilson, W ;
Grever, MR ;
Byrd, JC ;
Botstein, D ;
Brown, PO ;
Staudt, LM .
NATURE, 2000, 403 (6769) :503-511
[5]
Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays [J].
Alon, U ;
Barkai, N ;
Notterman, DA ;
Gish, K ;
Ybarra, S ;
Mack, D ;
Levine, AJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (12) :6745-6750
[6]
Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses [J].
Amundson, SA ;
Bittner, M ;
Chen, YD ;
Trent, J ;
Meltzer, P ;
Fornace, AJ .
ONCOGENE, 1999, 18 (24) :3666-3672
[7]
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer [J].
Anzick, SL ;
Kononen, J ;
Walker, RL ;
Azorsa, DO ;
Tanner, MM ;
Guan, XY ;
Sauter, G ;
Kallioniemi, OP ;
Trent, JM ;
Meltzer, PS .
SCIENCE, 1997, 277 (5328) :965-968
[8]
Gene expression informatics - it's all in your mine [J].
Bassett, DE ;
Eisen, MB ;
Boguski, MS .
NATURE GENETICS, 1999, 21 (Suppl 1) :51-55
[9]
The human CAS (cellular apoptosis susceptibility) gene mapping on chromosome 20q13 is amplified in BT474 breast cancer cells and part of aberrant chromosomes in breast and colon cancer cell lines [J].
Brinkmann, U ;
Gallo, M ;
Polymeropoulos, MH ;
Pastan, I .
GENOME RESEARCH, 1996, 6 (03) :187-194
[10]
Hormone therapy failure in human prostate cancer:: Analysis by complementary DNA and issue microarrays [J].
Bubendorf, L ;
Kolmer, M ;
Kononen, J ;
Koivisto, P ;
Mousses, S ;
Chen, YD ;
Mahlamäki, E ;
Schraml, P ;
Moch, H ;
Willi, N ;
Elkahloun, AG ;
Pretlow, TG ;
Gasser, TC ;
Mihatsch, MJ ;
Sauter, G ;
Kallioniemi, OP .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1999, 91 (20) :1758-1764