The use of intracytoplasmic sperm injection with electroejaculates from anejaculatory men

被引:34
作者
Chung, PH [1 ]
Palermo, G
Schlegel, PN
Veeck, LL
Eid, JF
Rosenwaks, Z
机构
[1] Cornell Univ, Med Ctr, New York Hosp, Ctr Reprod Med & Infertil,Dept Obstet & Gynecol, New York, NY 10021 USA
[2] Cornell Univ, Med Ctr, New York Hosp, James Buchanan Brady Fdn,Dept Urol, New York, NY 10021 USA
关键词
anejaculation; electroejaculation; ICSI; IVF;
D O I
10.1093/humrep/13.7.1854
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Electroejaculation has been successfully used for sperm procurement in anejaculatory men desiring fertility. However, electroejaculates typically have normal sperm numbers but poor motility, morphology, and functional deficiencies, Here we report the pregnancy outcome of a series of couples undergoing combined electroejaculation and in-vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI). In all, 13 couples underwent a total of 18 cycles. The aetiologies of anejaculation included history of retroperitoneal lymph node dissection for testicular cancers, spinal cord injury and psychogenic causes. ICSI was performed on 192 oocytes, resulting in a fertilization rate of 75.5%. A total of 15 embryo transfers were performed using a total of 51 embryos. Clinical pregnancy rate, as defined by positive fetal heart rate(s) using vaginal sonography, was 55.6% per retrieval; implantation rate was 33.3% per embryo. These rates appear to be similar to those obtained in standard IVF for non-male factor infertility, or ICSI for male factor infertility, The use of ICSI for electroejaculates undoubtedly provides these couples with the highest chance of pregnancy.
引用
收藏
页码:1854 / 1858
页数:5
相关论文
共 23 条
[1]   SEXUAL DYSFUNCTION AND ELECTROEJACULATION IN MEN WITH SPINAL-CORD INJURY - REVIEW [J].
BENNETT, CJ ;
SEAGER, SW ;
VASHER, EA ;
MCGUIRE, EJ .
JOURNAL OF UROLOGY, 1988, 139 (03) :453-457
[2]   EVALUATION AND TREATMENT OF INFERTILITY IN SPINAL-CORD INJURED MEN THROUGH RECTAL PROBE ELECTROEJACULATION [J].
BUCH, JP ;
ZORN, BH .
JOURNAL OF UROLOGY, 1993, 149 (05) :1350-1354
[3]   Correlation between semen parameters of electroejaculates and achieving pregnancy by intrauterine insemination [J].
Chung, PH ;
Verkauf, BS ;
Mola, R ;
Skinner, L ;
Eichberg, RD ;
Maroulis, GB .
FERTILITY AND STERILITY, 1997, 67 (01) :129-132
[4]  
CHUNG PH, 1995, FERTIL STERIL, V64, P1
[5]  
Chung PH, 1996, OBSTET GYNECOL, V87, P22
[6]   IMPLANTATION ENHANCEMENT BY SELECTIVE ASSISTED HATCHING USING ZONA DRILLING OF HUMAN EMBRYOS WITH POOR PROGNOSIS [J].
COHEN, J ;
ALIKANI, M ;
TROWBRIDGE, J ;
ROSENWAKS, Z .
HUMAN REPRODUCTION, 1992, 7 (05) :685-691
[7]  
DAHLBERG A, 1995, HUM REPROD, V10, P2305
[8]  
DAVIS OK, 1996, REPROD ENDOCRINOLOGY, P2319
[9]   FUNCTIONAL-CHARACTERISTICS OF SPERM OBTAINED BY ELECTROEJACULATION [J].
DENIL, J ;
OHL, DA ;
MENGE, AC ;
KELLER, LM ;
MCCABE, M .
JOURNAL OF UROLOGY, 1992, 147 (01) :69-72
[10]  
Denil J, 1996, HUM REPROD, V11, P1247