The great escape: structure and function of the autotransporter proteins

被引：418

作者：

Henderson, IR ^{[1
]}

Navarro-Garcia, F

Nataro, JP

机构：

[1] Univ Maryland, Sch Med, Dept Med, Ctr Vaccine Dev, Baltimore, MD 21201 USA

[2] Univ Maryland, Sch Med, Dept Pediat, Ctr Vaccine Dev, Baltimore, MD 21201 USA

[3] Univ Nacl Autonoma Mexico, Fac Med, Dept Publ Hlth, Mexico City 04510, DF, Mexico

来源：

TRENDS IN MICROBIOLOGY | 1998年 / 6卷 / 09期

关键词：

D O I：

10.1016/S0966-842X(98)01318-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The autotransporters, a family of secreted proteins from Gram-negative bacteria, possess an overall unifying structure comprising three functional domains: the amino-terminal leader sequence, the secreted mature protein (passenger domain) and a carboxy-terminal (beta-) domain that forms a beta-barrel pore to allow secretion of the passenger protein. Members of this family have been implicated as important or putative virulence factors in many Gram-negative pathogens.

引用

页码：370 / 378

页数：9

共 46 条

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