Recurrence after Treatment for Pulmonary Multidrug-Resistant Tuberculosis

被引：23

作者：

Becerra, Mercedes C. ^{[1
,2
]}

Appleton, Sasha C. ^{[1
,2
,3
]}

Franke, Molly F. ^{[1
,2
]}

Chalco, Katiuska ^{[2
]}

Bayona, Jaime ^{[1
,2
]}

Murray, Megan B. ^{[3
,4
]}

Mitnick, Carole D. ^{[1
,2
]}

机构：

[1] Harvard Univ, Sch Med, Dept Global Hlth & Social Med, Boston, MA 02115 USA

[2] Harvard Univ, Sch Publ Hlth, Socios Salud Sucursal Peru Partners Hlth, Boston, MA 02115 USA

[3] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

[4] Brigham & Womens Hosp, Div Global Hlth Equ, Boston, MA 02115 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2010年 / 51卷 / 06期

基金：

比尔及梅琳达.盖茨基金会;

关键词：

FOLLOW-UP;

D O I：

10.1086/655892

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We estimated the proportion of recurrence within 2 years among adults cured by individualized multidrug-resistant tuberculosis regimens in Peru. Among 310 individuals with at least 24 months of follow-up, 16 experienced an episode of recurrent tuberculosis. If we assume the worst for treatment effectiveness-that all 16 episodes were caused by the original tuberculosis strain-then 5.2% (95% confidence interval, 3.0%-8.2%) experienced true relapse. This is an upper-bound estimate of relapse on which new regimens must improve.

引用

页码：709 / 711

页数：3

共 14 条

[1] Outcome of pulmonary multidrug-resistant tuberculosis: a 6-yr follow-up study [J].

Chiang, C-Y. ;

Enarson, D. A. ;

Yu, M-C. ;

Bai, K-J. ;

Huang, R-M. ;

Hsu, C-J. ;

Suo, J. ;

Lin, T-P. .

EUROPEAN RESPIRATORY JOURNAL, 2006, 28 (05) :980-985

[2] The Diarylquinoline TMC207 for Multidrug-Resistant Tuberculosis [J].

Diacon, Andreas H. ;

Pym, Alexander ;

Grobusch, Martin ;

Patientia, Ramonde ;

Rustomjee, Roxana ;

Page-Shipp, Liesl ;

Pistorius, Christoffel ;

Krause, Rene ;

Bogoshi, Mampedi ;

Churchyard, Gavin ;

Venter, Amour ;

Allen, Jenny ;

Palomino, Juan Carlos ;

De Marez, Tine ;

van Heeswijk, Rolf P. G. ;

Lounis, Nacer ;

Meyvisch, Paul ;

Verbeeck, Johan ;

Parys, Wim ;

de Beule, Karel ;

Andries, Koen ;

Mc Neeley, David F. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (23) :2397-2405

[3]

Escudero E, 2006, INT J TUBERC LUNG D, V10, P409

[4]

Fox W, 1999, INT J TUBERC LUNG D, V3, pS231

[5]

Fraser HSF, 2002, AMIA 2002 SYMPOSIUM, PROCEEDINGS, P270

[6] Treatment Outcomes and Long-term Survival in Patients with Extensively Drug-resistant Tuberculosis [J].

Kim, Doh Hyung ;

Kim, Hee Jin ;

Park, Seung-Kyu ;

Kong, Suck-Jun ;

Kim, Young Sam ;

Kim, Tae-Hyung ;

Kim, Eun Kyung ;

Lees, Ki Man ;

Lee, Sung Soon ;

Park, Jae Seuk ;

Koh, Won-Jung ;

Lee, Chang-Hoon ;

Kim, Ji Yeon ;

Shim, Tae Sun .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2008, 178 (10) :1075-1082

[7]

Laserson KF, 2005, INT J TUBERC LUNG D, V9, P640

[8] Comprehensive treatment of extensively drug-resistant tuberculosis [J].

Mitnick, Carole D. ;

Shin, Sonya S. ;

Seung, Kwonjune J. ;

Rich, Michael L. ;

Atwood, Sidney S. ;

Furin, Jennifer J. ;

Fitzmaurice, Garrett M. ;

Alcantara Viru, Felix A. ;

Appleton, Sasha C. ;

Bayona, Jaime N. ;

Bonilla, Cesar A. ;

Chalco, Katiuska ;

Choi, Sharon ;

Franke, Molly F. ;

Fraser, Hamish S. F. ;

Guerra, Dalia ;

Hurtado, Rocio M. ;

Jazayeri, Darius ;

Joseph, Keith ;

Llaro, Karim ;

Mestanza, Lorena ;

Mukherjee, Joia S. ;

Munoz, Maribel ;

Palacios, Eda ;

Sanchez, Epifanio ;

Sloutsky, Alexander ;

Becerra, Mercedes C. .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (06) :563-574

[9] Randomized trials to optimize treatment of multidrug-resistant tuberculosis [J].

Mitnick, Carole D. ;

Castro, Kenneth G. ;

Harrington, Mark ;

Sacks, Leonard V. ;

Burman, William .

PLOS MEDICINE, 2007, 4 (11) :1730-1734

[10] Programmes and principles in treatment of multidrug-resistant tuberculosis [J].

Mukherjee, JS ;

Rich, ML ;

Socci, AR ;

Joseph, JK ;

Virú, FA ;

Shin, SS ;

Furin, JJ ;

Becerra, MC ;

Barry, DJ ;

Kim, JY ;

Bayona, J ;

Farmer, P ;

Fawzi, MCS ;

Seung, KJ .

LANCET, 2004, 363 (9407) :474-481

← 1 2 →