Surface thermodynamics study of monolayers formed with heteroacid phospholipids of biological interest

被引：28

作者：

Domènech, O

Torrent-Burgué, J

Merino, S

Sanz, F

Montero, MT

Hernández-Borrell, J

机构：

[1] Univ Barcelona, Dept Fisicoquim, E-08028 Barcelona, Spain

[2] Ctr Bioelect & Nanobiociencia, CBEN, E-08028 Barcelona, Spain

[3] Univ Barcelona, Dept Quim Fis, E-08028 Barcelona, Spain

[4] UPC, Dept Engn Quim, Terrassa 08222, Spain

来源：

COLLOIDS AND SURFACES B-BIOINTERFACES | 2005年 / 41卷 / 04期

关键词：

monolayer; surface pressure isotherms; phospholipids; equation state; thermodynamic analysis;

D O I：

10.1016/j.colsurfb.2004.12.012

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The interaction of 1-palmitoy-2-oleoyl-sn-glycero-3-phosphocoline (POPC) and 1-palmitoy-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE), two of the major components in biological membranes, were investigated using the monolayer technique at the air-water interface. The pressure-area isotherms indicate that both phospholipids are miscible through all range of compositions. POPE-POPC form stable mixtures, with a minimum for the Gibbs energy of mixing at X-POPC = 0.4. A virial equation of state was fitted to the experimental values. Positive values found for the second virial coefficient indicate repulsion between POPC and POPE. The interaction parameter was evaluated which indicated that a corresponding decrease in the repulsion occurs when POPC molar fraction is low. This effect suggests the existence of hydrogen bonds between POPE and the water beneath the interface. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：233 / 238

页数：6

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