Recurrent ventriculoperitoneal shunt infection caused by small-colony variants of Staphylococcus aureus

被引：39

作者：

Spanu, T

Romano, L

D'Inzeo, T

Masucci, L

Albanese, A

Papacci, F

Marchese, E

Sanguinetti, M

Fadda, G

机构：

[1] Univ Cattolica Sacro Cuore, Inst Microbiol, I-00168 Rome, Italy

[2] Univ Cattolica Sacro Cuore, Dept Neurosurg, I-00168 Rome, Italy

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 41卷 / 05期

关键词：

D O I：

10.1086/432577

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Phenotypic variants of Staphylococcus aureus may be misidentified by routine microbiological methods, and they may also respond poorly to antibacterial treatment. Using molecular methods, we identified small-colony variants of methicillin-resistant S. aureus (which were misidentified by 3 widely used automated identification systems as methicillin-susceptible coagulase-negative staphylococci) as the cause of recurrent ventriculoperitoneal shunt-related meningitis.

引用

收藏

页码：E48 / E52

页数：5

相关论文

共 20 条

[1] DETECTION OF STAPHYLOCOCCUS-AUREUS BY POLYMERASE CHAIN-REACTION AMPLIFICATION OF THE NUC GENE [J].

BRAKSTAD, OG ;

AASBAKK, K ;

MAELAND, JA .

JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (07) :1654-1660

[2] Decreased susceptibility to antibiotic killing of a stable small colony variant of Staphylococcus aureus in fluid phase and on fibronectin-coated surfaces [J].

Chuard, C ;

Vaudaux, PE ;

Proctor, RA ;

Lew, DP .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 39 (05) :603-608

[3] MULTIPLEX PCR FOR IDENTIFICATION OF METHICILLIN-RESISTANT STAPHYLOCOCCI IN THE CLINICAL LABORATORY [J].

GEHA, DJ ;

UHL, JR ;

GUSTAFERRO, CA ;

PERSING, DH .

JOURNAL OF CLINICAL MICROBIOLOGY, 1994, 32 (07) :1768-1772

[4] MOLECULAR TYPING OF STAPHYLOCOCCUS-AUREUS ON THE BASIS OF COAGULASE GENE POLYMORPHISMS [J].

GOH, SH ;

BYRNE, SK ;

ZHANG, JL ;

CHOW, AW .

JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (07) :1642-1645

[5] Persistent infection with small colony variant strains of Staphylococcus aureus in patients with cystic fibrosis [J].

Kahl, B ;

Herrmann, M ;

Everding, AS ;

Koch, HG ;

Becker, K ;

Harms, E ;

Proctor, RA ;

Peters, G .

JOURNAL OF INFECTIOUS DISEASES, 1998, 177 (04) :1023-1029

[6] Evaluation of two chromogenic agar media for recovery and identification of Staphylococcus aureus small-colony variants [J].

Kipp, F ;

Kahl, BC ;

Becker, K ;

Baron, EJ ;

Proctor, RA ;

Peters, G ;

von Eiff, C .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (04) :1956-1959

[7] Evaluation of different methods to detect methicillin resistance in small-colony variants of Staphylococcus aureus [J].

Kipp, F ;

Becker, K ;

Peters, G ;

von Eiff, C .

JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (03) :1277-1279

[8] Detection of Staphylococcus aureus by 16S rRNA directed in situ hybridisation in a patient with a brain abscess caused by small colony variants [J].

Kipp, F ;

Ziebuhr, W ;

Becker, K ;

Krimmer, V ;

Höss, N ;

Peters, G ;

von Eiff, C .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2003, 74 (07) :1000-1002

[9] Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States:: Establishing a national database [J].

McDougal, LK ;

Steward, CD ;

Killgore, GE ;

Chaitram, JM ;

McAllister, SK ;

Tenover, FC .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (11) :5113-5120

[10] Risk factors for pediatric bentriculoperitoneal shunt infection and predictors of infectious pathogens [J].

McGirt, MJ ;

Zaas, A ;

Fuchs, HE ;

George, TM ;

Kaye, K ;

Sexton, DJ .

CLINICAL INFECTIOUS DISEASES, 2003, 36 (07) :858-862