Synthetic study of substituted arylsulfonylphenylbenzamides

被引:5
作者
Gong, DH
Li, JF
Yuan, CY
Yuan, JY
机构
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
[2] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA
关键词
aryl sulfones; benzomides; structure-activity relationship;
D O I
10.1081/SCC-200046496
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
For the structure-activity relationship, a series of substituted arylsulfonyl-phenylbenzamides is reported.
引用
收藏
页码:55 / 66
页数:12
相关论文
共 28 条
[1]  
Adams R., 1975, ORG SYNTH, V5, P107
[2]   REACTIONS OF ORGANOLITHIUM COMPOUNDS WITH SULFONATE ESTERS - NOVEL SULFONE SYNTHESIS [J].
BAARSCHERS, WH .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1976, 54 (19) :3056-3059
[3]   Lipophilicity behavior of model and medicinal compounds containing a sulfide, sulfoxide, or sulfone moiety [J].
Caron, G ;
Gaillard, P ;
Carrupt, PA ;
Testa, B .
HELVETICA CHIMICA ACTA, 1997, 80 (02) :449-462
[5]   Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL [J].
Degterev, A ;
Lugovskoy, A ;
Cardone, M ;
Mulley, B ;
Wagner, G ;
Mitchison, T ;
Yuan, JY .
NATURE CELL BIOLOGY, 2001, 3 (02) :173-182
[6]   BH3-domain mimetic compound BH3I-2′ induces rapid damage to the inner mitochondrial membrane prior to the cytochrome c release from mitochondria [J].
Feng, WY ;
Liu, FT ;
Patwari, Y ;
Agrawal, SG ;
Newland, AC ;
Jia, L .
BRITISH JOURNAL OF HAEMATOLOGY, 2003, 121 (02) :332-340
[7]  
FOURNIER JP, 1982, EUR J MED CHEM, V17, P53
[8]  
Gilman H., 1925, J AM CHEM SOC, V47, P2047, DOI [10.1021/ja01684a040, DOI 10.1021/JA01684A040]
[9]   DIRECT CONVERSION OF (1S,2S)-2-AMINO-1-[(4-METHYLTHIO)PHENYL]-1,3-PROPANEDIOL INTO ITS ENANTIOMER FOR EFFICIENT SYNTHESIS OF THIAMPHENICOL AND FLORFENICOL [J].
GIORDANO, C ;
CAVICCHIOLI, S ;
LEVI, S ;
VILLA, M .
JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (21) :6114-6118
[10]   The mesomeric effect of the sulphoxide group [J].
Hammick, DL ;
Williams, RB .
JOURNAL OF THE CHEMICAL SOCIETY, 1938, :211-215